Research
Coming Soon…..
Coming Soon…
1. Integrated Antimicrobial Stewardship (IAS) Practice Statements for Indian Hospitals
Considering the importance of integrated antimicrobial stewardship (IAS) practices by each hospital and each healthcare worker (HCW), it is vital to have a practice statement from SASPI based on available evidence from the literature and a recently completed Delphi study under SASPI. This document is developed and finalized through a Delphi model where it was prepared by three Indian experts (An ID physician, A Pharmacologist and A Microbiologist) in the first phase, and shared with SASPI members with experts in the same field (at least one expert (HICC/AMSP member) from 31 tertiary care institutes/hospitals) for content validation and comments regarding the feasibility of their practices in the second phase, and lastly again verified by same three experts of the first phase and prepared the practice statements with consideration of all relevant comments by individual institute experts in third phase.
These practice statements (Box 1) are the baseline Indian practice guidance towards IAS practices to curtail AMR in tertiary care hospitals. Each Indian hospital is advocated to follow these practices. With time, through multi-centric participation under the banner of SASPI, these practices will be monitored and updated towards higher goals
2. Multicentric PPS 2023- ASPIRE II/ SASPI
Summary of the PPS Survey Conducted by SASPI (May-August 2023)
The Point Prevalence Survey (PPS) conducted by the Society of Antimicrobial Stewardship Practices in India (SASPI) from May to August 2023 aimed to assess the use of antimicrobials across eight tertiary care centers in India. The survey was conducted in accordance with WHO methodology, tailored to meet local needs and guidelines, and received ethical approval from all participating institutions.
Participating Centers
The survey included eight prominent medical institutions:
- Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh
- All India Institute of Medical Sciences (AIIMS), Bhopal
- AIIMS, Rishikesh
- AIIMS, Bathinda
- AIIMS, Jodhpur
- AIIMS, Gorakhpur
- AIIMS, Raebareli
- Government Medical College, Baroda
PGIMER, Chandigarh, served as the central coordinating site.
Methodology
The survey was conducted over ten to fourteen days in each center, focusing on all inpatient wards, including intensive care units and surgical wards. Data was collected on all patients admitted before 8:00 a.m. on the survey day, ensuring comprehensive coverage of antimicrobial usage. Exclusion criteria included outpatients, late admissions, and patients in day care or emergency observation.
Data Collection
Data were collected using predesigned Google Forms, which facilitated user-friendly input and ensured cross-platform compatibility. The forms captured ward-level information and individual patient data, including demographics and details of antimicrobial therapy. Data sources included medical records, treatment charts, and direct consultations with floor residents or consultants. Anonymized patient identifiers were used to maintain confidentiality.
Training and Oversight
Training sessions were conducted by the central coordinating site to guide participating centers in data collection and the use of forms. Each site was required to complete pilot forms and verify data accuracy through cross-checking with source documents.
Data Analysis
Real-time data consolidation occurred via Google Drive, with a focus on various parameters:
- The percentage of patients on antimicrobials
- Usage of antimicrobials categorized by purpose (empirical, prophylactic, definitive)
- Antibiotic prescription patterns aligned with the WHO-AWaRe classification
- Specifics on community-acquired and hospital-acquired infections
Additionally, a subset of 450 prescriptions was evaluated for appropriateness using the AMRAT-2 tool, assessing dosage, duration, and indication.
Current status: Currently the manuscript is under review process by journal.
Timeline:
Initiation: May – August 2023
Data cleaning: November –December 2023
Data Analysis- Jan 2024- July 2024
Manuscript writing, authors signage and other documents collection August-September 2024
Submission to Journal- November 2024
Currently Under review